52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.10%⁩, the S&P 500 is ⁦-0.40%⁩, and the Nasdaq Composite is ⁦-0.91%⁩. Across individual stocks, 1,983 are advancing while 3,131 are declining, suggesting a mixed market tone.

Dow Jones

52,347.55

Change

+50.46+0.10%

S&P 500

7,561.67

Change

-30.73-0.40%

Nasdaq Composite

25,136.273

Change

-229.82-0.91%

24H Gainers

1,983

24H Losers

3,131

52 Week Gainers

Large Cap Small Cap 52 Week Gainers 52 Week Losers Semiconductor Software Biotech Bank

#	Stock					52 Week Range
4251	Nerdy Inc.NRDY	$5.57	-4.25%	20.88K	$51.34M	$5.37 - $22.35	0.00%
4252	Evommune, Inc.EVMN	$7.64	-4.86%	694.00K	$312.84M	$4.94 - $33.20	0.00%
4253	Artivion, Inc.AORT	$19.10	-1.55%	447.96K	$931.34M	$18.96 - $48.25	0.00%
4254	Electra Battery Materials CorporationELBM	$0.40	-2.84%	248.77K	$43.13M	$0.37 - $1.25	0.00%
4255	Greenpro Capital Corp.GRNQ	$7.24	-0.82%	7.79K	$13.28M	$5.51 - $31.80	0.00%
4256	ImageneBio, Inc.IMA	$3.48	-1.30%	3.65K	$39.56M	$3.23 - $8.70	0.00%
4257	Beamr Imaging Ltd.BMR	$0.86	+2.08%	53.10K	$13.36M	$0.85 - $2.51	0.00%
4258	Zevia PBCZVIA	$1.07	+3.77%	406.44K	$77.59M	$1.03 - $2.75	0.00%
4259	CytoMed Therapeutics LimitedGDTC	$0.80	-0.13%	8.91K	$9.45M	$0.68 - $2.29	0.00%
4260	Ionis Pharmaceuticals, Inc.IONS	$29.05	+6.41%	4.70M	$4.83B	$27.28 - $86.74	0.00%
4261	Coherus Oncology, Inc.CHRS	$0.52	-2.97%	4.17M	$80.96M	$0.51 - $2.62	0.00%
4262	Atlantic American Corp.AAME	$1.26	+6.72%	29.80K	$25.62M	$1.01 - $3.24	0.03%
4263	Coursera, Inc.COUR	$3.50	-0.84%	4.12M	$887.82M	$3.45 - $8.89	0.00%
4264	CorMedix Inc.CRMD	$4.66	-3.82%	2.10M	$362.91M	$4.66 - $13.02	0.00%
4265	International Money Express, Inc.IMXI	$6.28	-1.88%	1.28M	$189.58M	$5.84 - $15.95	0.00%
4266	CoinShares PLCCSHR	$3.57	-0.28%	169.00K	$484.95M	$3.46 - $10.43	0.00%
4267	Ebang International Holdings Inc.EBON	$1.63	-1.81%	5.28K	$8.13M	$1.35 - $4.16	0.00%
4268	Fair Isaac CorporationFICO	$719.93	+0.39%	363.82K	$15.55B	$586.05 - $1,858.91	0.00%
4269	UP Fintech Holding Ltd AmericanTIGR	$4.14	+5.74%	2.36M	$713.00M	$3.61 - $11.35	0.00%
4270	Janux Therapeutics, Inc.JANX	$11.36	-1.26%	603.15K	$694.64M	$11.16 - $35.34	0.00%
4271	Burford Capital LimitedBUR	$3.60	+2.89%	1.49M	$791.64M	$2.86 - $10.10	0.08%
4272	Universe Pharmaceuticals Inc.UPC	$1.54	+4.39%	12.97K	$870.36K	$1.33 - $17.96	0.00%
4273	WM Technology, Inc.MAPS	$0.00	0.00%	0	$0	$0.16 - $1.21	0.05%
4274	NuSkin Enterprises, Inc.NUS	$4.04	+0.50%	344.96K	$196.41M	$3.87 - $11.67	0.06%
4275	Exascale Labs Holdings Inc.XLAB	$2.12	-6.39%	21.32M	$66.91M	$0.78 - $7.39	0.00%
4276	ACRES Commercial Realty Corp.ACR	$8.85	-8.76%	56.37K	$63.12M	$8.84 - $24.61	0.16%
4277	Biote Corp.BTMD	$1.07	+3.40%	63.17K	$30.74M	$0.99 - $2.90	0.04%
4278	Anfield Energy Inc.AEC	$2.74	-1.08%	39.33K	$54.68M	$2.67 - $10.24	0.00%
4279	BCP Investment CorporationBCIC	$5.15	-8.20%	192.05K	$63.78M	$5.07 - $13.44	0.29%
4280	GSI TechnologyGSIT	$3.08	-4.04%	448.27K	$118.56M	$2.93 - $13.00	0.00%
4281	AlTi Global, Inc.ALTI	$1.59	-5.95%	624.22K	$183.08M	$1.25 - $5.45	0.00%
4282	Spero Therapeutics, Inc.SPRO	$1.00	-0.80%	351.07K	$58.23M	$0.96 - $3.08	0.00%
4283	Lucky Strike Entertainment CorporationLUCK	$3.44	+12.18%	287.10K	$278.22M	$2.93 - $9.59	0.08%
4284	Centrus Energy Corp.LEU	$103.79	-2.04%	581.72K	$2.07B	$84.86 - $345.60	0.00%
4285	Rein Therapeutics, Inc.RNTX	$0.55	-2.82%	485.79K	$47.62M	$0.51 - $2.10	0.00%
4286	Phathom Pharmaceuticals, Inc.PHAT	$6.07	-2.57%	1.40M	$493.52M	$5.01 - $18.31	0.00%
4287	Foxx Development Holdings Inc.FOXX	$1.33	-5.48%	5.48K	$9.69M	$1.03 - $7.90	0.00%
4288	QVC Group, Inc.QVCG	$7.96	+2.77%	1.19M	$403.00M	$6.80 - $20.00	0.00%
4289	D-Wave Quantum Inc.QBTS	$9.55	-2.95%	10.09M	$3.52B	$8.48 - $32.39	0.00%
4290	Coastal Financial CorporationCCB	$42.61	-1.43%	158.60K	$651.30M	$35.56 - $120.05	0.00%
4291	Pliant Therapeutics, Inc.PLRX	$0.70	-5.88%	859.38K	$43.28M	$0.69 - $1.80	0.00%
4292	Altimmune, Inc.ALT	$1.65	+1.86%	3.30M	$320.57M	$1.58 - $6.44	0.00%
4293	Metagenomi Therapeutics, Inc.MGX	$0.69	-3.35%	117.77K	$26.03M	$0.60 - $1.87	0.00%
4294	Rezolve AI PLCRZLV	$1.20	-4.00%	12.80M	$403.26M	$1.16 - $4.97	0.00%
4295	Connect Biopharma Holdings LimitedCNTB	$0.68	+1.59%	219.80K	$42.70M	$0.64 - $3.82	0.00%
4296	Flutter Entertainment plcFLUT	$81.10	-1.02%	1.41M	$14.10B	$72.56 - $229.86	0.00%
4297	ONE Nuclear Energy Inc.ONEN	$1.40	-3.31%	48.84K	$149.52M	$1.22 - $3.65	0.00%
4298	Aware Inc.AWRE	$0.94	+3.28%	19.59K	$20.67M	$0.82 - $2.52	0.00%
4299	GeneDx Holdings Corp.WGS	$52.36	+0.87%	1.01M	$1.56B	$32.21 - $170.87	0.00%
4300	Annovis Bio, Inc.ANVS	$0.92	+9.73%	2.12M	$39.54M	$0.62 - $5.50	0.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?

These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.

How is the 52-week gain calculated?

It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.

Which stock has gained the most over 52 weeks?

Nerdy Inc. (NRDY) currently leads with a 52-week gain of 58.05% as of 2026-11-13 22:49 UTC.

Why use a 52-week stock performance ranking?

It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.

Does strong 52-week performance guarantee future gains?

No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.

How is this different from the daily Top Gainers list?

The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

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Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.