52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.09%⁩, the S&P 500 is ⁦-0.42%⁩, and the Nasdaq Composite is ⁦-0.91%⁩. Across individual stocks, 2,010 are advancing while 3,104 are declining, suggesting a mixed market tone.

Dow Jones

52,342.03

Change

+44.94+0.09%

S&P 500

7,560.87

Change

-31.53-0.42%

Nasdaq Composite

25,135.961

Change

-230.132-0.91%

24H Gainers

2,010

24H Losers

3,104

52 Week Gainers

Large Cap Small Cap 52 Week Gainers 52 Week Losers Semiconductor Software Biotech Bank

#	Stock					52 Week Range
101	Oportun Financial CorporationOPRT	$11.58	-0.26%	21.64K	$533.42M	$4.03 - $13.34	0.00%
102	Rackspace Technology, Inc.RXT	$2.75	-8.47%	1.16M	$702.17M	$0.39 - $8.60	0.00%
103	CHATHAM LODGING TRUSTCLDT	$15.89	-1.29%	26.66K	$740.02M	$6.38 - $16.61	0.04%
104	Turn Therapeutics Inc.TTRX	$9.69	-5.46%	4.74K	$320.99M	$2.57 - $16.45	0.00%
105	Starz Entertainment Corp.STRZ	$25.55	-1.86%	12.87K	$461.15M	$8.40 - $32.58	0.00%
106	Kiniksa Pharmaceuticals International, plcKNSA	$95.12	-1.01%	69.85K	$4.65B	$37.02 - $99.31	0.00%
107	Enliven Therapeutics, Inc.ELVN	$47.70	-1.07%	15.43K	$3.51B	$14.79 - $62.32	0.00%
108	Replimune Group, Inc.REPL	$21.09	-3.25%	224.32K	$2.00B	$1.50 - $23.54	0.00%
109	FIGS, Inc.FIGS	$22.04	-1.46%	606.06K	$3.47B	$8.95 - $23.77	0.00%
110	MarineMax, Inc.HZO	$52.81	+0.07%	55.29K	$1.17B	$21.42 - $52.89	0.00%
111	Ichor HoldingsICHR	$34.63	-5.18%	145.32K	$1.30B	$14.07 - $113.58	0.00%
112	Cheesecake Factory (The)CAKE	$106.77	+2.10%	127.95K	$5.32B	$43.07 - $118.63	0.01%
113	Maravai LifeSciences Holdings, Inc.MRVI	$7.56	-1.37%	169.98K	$1.13B	$2.80 - $9.42	0.00%
114	Amylyx Pharmaceuticals, Inc.AMLX	$28.88	-2.55%	134.13K	$3.22B	$10.83 - $41.14	0.00%
115	Polyrizon Ltd.PLRZ	$10.74	-1.38%	1.01K	$26.76M	$2.88 - $18.20	0.00%
116	AMN Healthcare ServicesAMN	$37.19	-0.32%	11.18K	$1.44B	$14.97 - $49.62	0.00%
117	Roma Green Finance LimitedROMA	$6.34	-4.72%	997	$377.40M	$1.16 - $11.77	0.00%
118	Applied Optoelectronics, Inc.AAOI	$48.31	-7.15%	3.16M	$4.09B	$18.50 - $233.67	0.00%
119	Axogen, Inc.AXGN	$55.48	-0.23%	100.90K	$3.31B	$23.00 - $59.72	0.00%
120	Frequency Electronics, Inc.FEIM	$63.74	-4.69%	17.50K	$718.56M	$26.05 - $89.76	0.00%
121	Acadia Healthcare Company, Inc.ACHC	$37.04	-1.94%	149.00K	$3.44B	$11.43 - $39.70	0.00%
122	Ibotta, Inc.IBTA	$57.47	+0.76%	46.08K	$1.18B	$19.10 - $66.39	0.00%
123	Stagwell Inc.STGW	$11.09	+0.94%	78.43K	$2.75B	$4.29 - $12.26	0.00%
124	Park-Ohio Holdings Corp.PKOH	$46.22	-0.99%	3.75K	$669.70M	$18.69 - $53.30	0.01%
125	Xeris Biopharma Holdings, Inc.XERS	$16.43	-0.96%	170.53K	$3.00B	$5.25 - $16.88	0.00%
126	Quhuo LimitedQH	$2.94	-1.51%	1.59K	$8.17M	$0.07 - $12.81	0.00%
127	CryoPort, Inc.CYRX	$19.81	-1.17%	23.77K	$1.00B	$7.61 - $21.78	0.00%
128	Universal Electronics Inc.UEIC	$6.71	+0.91%	16.72K	$86.47M	$2.69 - $6.89	0.00%
129	Jerash Holdings (US), Inc.JRSH	$7.25	-0.54%	104.55K	$92.09M	$2.85 - $7.90	0.03%
130	MBX Biosciences, Inc.MBX	$54.02	-0.87%	18.84K	$2.60B	$23.07 - $72.64	0.00%
131	Hyperliquid Strategies Inc.PURR	$8.71	-1.31%	3.31M	$1.81B	$3.01 - $14.76	0.00%
132	Commercial Vehicle Group, Inc.CVGI	$3.48	-0.43%	44.55K	$141.12M	$1.36 - $5.88	0.00%
133	Edgewise Therapeutics, Inc.EWTX	$45.38	-1.96%	46.65K	$4.97B	$19.76 - $48.78	0.00%
134	Encore Capital Group, Inc.ECPG	$108.47	-0.74%	29.38K	$2.26B	$47.49 - $126.74	0.00%
135	Okeanis Eco Tankers Corp.ECO	$86.15	-1.63%	279.69K	$3.35B	$31.75 - $102.56	0.00%
136	FatPipe, Inc.FATN	$4.86	+3.58%	4.25K	$68.64M	$1.31 - $8.61	0.00%
137	Quantum CorporationQMCO	$15.51	-6.01%	155.80K	$611.37M	$4.19 - $35.65	0.00%
138	Cracker Barrel Old Country Store, Inc,.CBRL	$66.17	+2.51%	50.05K	$1.48B	$24.85 - $73.67	0.02%
139	The GEO Group, Inc.GEO	$31.84	-0.53%	144.61K	$4.21B	$12.51 - $33.31	0.00%
140	Oscar Health, Inc.OSCR	$30.46	-3.41%	389.88K	$8.33B	$10.69 - $38.50	0.00%
141	Prelude Therapeutics IncorporatedPRLD	$3.29	-3.69%	36.59K	$262.55M	$1.29 - $6.83	0.00%
142	LifeStance Health Group, Inc.LFST	$13.73	-2.47%	651.71K	$5.25B	$6.01 - $15.66	0.00%
143	Hamilton Beach Brands Holding CompanyHBB	$30.43	+0.77%	4.99K	$299.95M	$13.75 - $39.99	0.02%
144	Immix Biopharma, Inc.IMMX	$7.83	-3.47%	143.93K	$560.15M	$3.45 - $15.10	0.00%
145	BrightSpring Health Services, Inc.BTSG	$68.66	-3.25%	224.88K	$13.66B	$30.64 - $73.75	0.00%
146	PubMatic, Inc.PUBM	$19.80	+3.47%	174.17K	$738.69M	$6.15 - $19.82	0.00%
147	Satellogic Inc.SATL	$3.25	-7.10%	1.14M	$465.98M	$1.25 - $12.00	0.00%
148	Flexsteel IndustriesFLXS	$75.56	+1.52%	7.36K	$314.50M	$34.59 - $90.64	0.01%
149	Septerna, Inc.SEPN	$41.33	-1.72%	29.51K	$2.31B	$18.64 - $53.34	0.00%
150	Pyxis Tankers Inc.PXS	$5.76	+0.16%	21.90K	$58.97M	$2.62 - $8.34	0.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?

These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.

How is the 52-week gain calculated?

It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.

Which stock has gained the most over 52 weeks?

Oportun Financial Corporation (OPRT) currently leads with a 52-week gain of 140.17% as of 2026-11-13 21:22 UTC.

Why use a 52-week stock performance ranking?

It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.

Does strong 52-week performance guarantee future gains?

No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.

How is this different from the daily Top Gainers list?

The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

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Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.