Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More
100%+ PoR

52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.09%⁩, the S&P 500 is ⁦-0.42%⁩, and the Nasdaq Composite is ⁦-0.91%⁩. Across individual stocks, 1,994 are advancing while 3,120 are declining, suggesting a mixed market tone.

Dow Jones
52,342.03
Change
+44.94+0.09%
S&P 500
7,560.87
Change
-31.53-0.42%
Nasdaq Composite
25,135.961
Change
-230.132-0.91%
24H Gainers
1,994
24H Losers
3,120

52 Week Gainers

#Stock52 Week Range
51SAIHEAT LimitedSAIH$21.96+0.60%5.93K$26.25M$5.90 - $33.000.00%
52Bandwidth Inc.BAND$43.69-5.49%259.65K$1.33B$12.50 - $79.080.00%
53ImmunityBio, Inc.IBRX$6.01-0.99%12.57M$6.37B$1.95 - $12.430.00%
54American Well CorporationAMWL$11.77-2.41%44.20K$183.34M$3.71 - $15.160.00%
55Butterfly Network, Inc.BFLY$6.08-8.85%3.87M$1.50B$1.90 - $10.210.00%
56Sezzle Inc.SEZL$154.65-0.03%301.37K$5.22B$49.50 - $195.710.00%
57LB Pharmaceuticals Inc.LBRX$43.00+1.15%305.85K$1.45B$14.40 - $50.160.00%
58Vera Bradley, Inc.VRA$7.61+0.93%369.03K$218.44M$1.39 - $8.360.00%
59Lindblad Expeditions Holdings Inc.LIND$34.54+1.10%365.02K$2.27B$11.37 - $38.850.00%
60American Outdoor Brands, Inc.AOUT$18.57-1.79%59.67K$234.38M$6.26 - $19.500.00%
61Able View Global Inc.ABLV$2.29+0.45%62.29K$56.02M$0.54 - $2.960.00%
62Cumberland Pharmaceuticals Inc.CPIX$5.88-11.24%124.44K$88.18M$1.85 - $9.280.00%
63Relay Therapeutics, Inc.RLAY$18.10+0.11%1.22M$4.00B$6.04 - $21.270.00%
64Omeros CorporationOMER$17.49-2.81%575.89K$1.27B$6.24 - $21.240.00%
65RINGCENTRAL, INC.RNG$75.35-0.66%1.11M$5.63B$24.14 - $98.140.00%
66Kelly Services Inc.KELYB$24.75-0.39%105$81.56M$8.38 - $125.000.01%
67STAK Inc.STAK$1.53+1.65%8.09M$36.12M$0.29 - $12.000.00%
68Hinge Health, Inc.HNGE$115.34-4.63%1.12M$9.89B$30.08 - $126.400.00%
69Iridium Communications Inc.IRDM$45.86-0.59%503.38K$4.87B$15.64 - $57.180.01%
70Aehr Test SystemsAEHR$56.95-6.73%1.80M$1.86B$18.70 - $147.400.00%
71EuroDry LtdEDRY$36.27-14.35%89.60K$103.99M$12.30 - $73.070.00%
72Ultralife CorporationULBI$15.72-0.32%101.53K$262.03M$4.90 - $16.150.00%
73Elite Express Holding Inc.ETS$1.53+4.83%14.01K$64.15M$0.39 - $2.750.00%
74Revolution Medicines, Inc.RVMD$172.31-2.31%2.32M$37.27B$63.50 - $224.310.00%
75Glaukos CorporationGKOS$245.67-0.21%446.37K$14.54B$87.32 - $255.190.00%
76RXO, Inc.RXO$28.43+0.42%1.33M$4.69B$10.43 - $29.900.00%
77BBB Foods Inc.TBBB$70.02+2.99%1.65M$5.46B$25.84 - $70.120.00%
78Xencor, Inc.XNCR$37.11-2.75%780.12K$2.78B$10.38 - $40.600.00%
79Vestis CorporationVSTS$14.09-0.70%458.56K$1.86B$5.00 - $16.900.00%
80Lumentum Holdings Inc.LITE$596.72-4.48%3.46M$54.12B$215.35 - $1,143.000.00%
81Alto Neuroscience Inc.ANRO$29.64-3.53%532.31K$1.16B$10.80 - $37.480.00%
82Agencia Comercial Spirits LtdAGCC$14.11-2.57%53.43K$601.15M$5.24 - $25.730.00%
83Forum Energy Technologies, Inc.FET$76.87+0.07%103.63K$881.91M$28.68 - $91.990.00%
84Surrozen, Inc.SRZN$31.53-0.32%93.16K$366.07M$12.12 - $37.830.00%
85Dianthus Therapeutics, Inc.DNTH$91.89-0.67%464.95K$5.04B$34.29 - $117.880.00%
86Dell Technologies Inc.DELL$344.42-7.86%8.97M$108.64B$110.22 - $595.510.01%
87Andersen Group Inc.ANDG$60.14-8.19%944.21K$1.28B$18.12 - $68.410.00%
88MARRIOTT VACATIONS WORLDWIDE CORPORATIONVAC$116.89+1.58%285.46K$4.02B$44.58 - $131.340.03%
89Rackspace Technology, Inc.RXT$2.91-3.32%4.43M$742.70M$0.39 - $8.600.00%
90First Tracks Biotherapeutics, Inc.TRAX$47.05-3.39%389.92K$2.12B$14.72 - $54.780.00%
91Shattuck Labs, Inc.STTK$4.64-3.53%655.21K$465.89M$1.72 - $8.330.00%
92Trueblue, Inc.TBI$12.41+0.49%141.48K$378.28M$3.18 - $13.590.00%
93Penguin Solutions, Inc.PENG$47.37-5.37%1.20M$2.85B$16.04 - $89.860.00%
94Maase Inc.MAAS$10.01-2.63%19.95K$4.36B$3.71 - $24.900.00%
95Hongli Group Inc.HLP$4.14-7.22%430.70K$309.27M$0.34 - $4.900.00%
96SharkNinja, Inc.SN$226.22+2.84%1.02M$31.88B$83.21 - $232.760.00%
97Replimune Group, Inc.REPL$21.91-0.36%1.57M$2.08B$1.50 - $23.540.00%
98Amylyx Pharmaceuticals, Inc.AMLX$30.28+1.42%1.45M$3.37B$10.83 - $41.140.00%
99Oportun Financial CorporationOPRT$11.73-0.21%324.93K$540.52M$4.03 - $13.340.00%
100Globus Maritime LimitedGLBS$2.90+2.09%196.29K$62.61M$1.14 - $4.060.00%

BTC $81K: Catch the Next Move

Track ETH, SOL & TON rotation signals

BTC $81K: Catch the Next Move

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
SAIHEAT Limited (SAIH) currently leads with a 52-week gain of 208.86% as of 2026-11-13 21:22 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.