Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More
100%+ PoR

52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.10%⁩, the S&P 500 is ⁦-0.40%⁩, and the Nasdaq Composite is ⁦-0.91%⁩. Across individual stocks, 1,977 are advancing while 3,137 are declining, suggesting a mixed market tone.

Dow Jones
52,347.55
Change
+50.46+0.10%
S&P 500
7,561.67
Change
-30.73-0.40%
Nasdaq Composite
25,136.273
Change
-229.82-0.91%
24H Gainers
1,977
24H Losers
3,137

52 Week Losers

#Stock52 Week Range
1151TPG Mortgage Investment Trust, Inc.MITT$4.25+1.67%501.76K$135.32M$4.05 - $9.270.38%
1152Collegium Pharmaceutical, Inc.COLL$25.34+1.60%302.47K$825.12M$21.43 - $50.790.00%
1153Chimera Investment Corp.CIM$6.59-0.75%2.08M$551.50M$6.38 - $14.180.39%
1154MARA Holdings, Inc.MARA$6.99-2.92%39.88M$2.70B$5.69 - $16.430.00%
1155ClearPoint Neuro, Inc.CLPT$8.48-0.93%410.03K$271.82M$8.27 - $19.630.00%
1156Kura Sushi USA, Inc.KRUS$26.08-1.68%266.98K$290.80M$25.08 - $80.840.00%
1157Hims & Hers Health, Inc.HIMS$19.73-1.47%9.22M$4.44B$13.74 - $40.990.00%
1158T1 Energy Inc.TE$1.91-6.35%41.67M$572.34M$1.60 - $12.490.00%
1159BullishBLSH$22.48-3.58%1.03M$3.57B$20.06 - $48.930.00%
1160Vuzix CorporationVUZI$1.34-26.90%3.88M$113.37M$1.30 - $5.620.00%
1161NeOnc Technologies Holdings, Inc.NTHI$4.92+1.86%228.96K$129.01M$2.50 - $11.800.00%
1162Cabaletta Bio, Inc.CABA$1.28-3.76%2.86M$217.70M$1.18 - $4.230.00%
1163T Stamp Inc.IDAI$2.56+1.79%9.92K$14.54M$1.17 - $5.280.00%
1164USA Rare Earth, Inc.USAR$8.16+1.05%17.13M$3.06B$6.84 - $32.800.00%
1165TechTarget, Inc.TTGT$2.81+0.36%425.22K$200.91M$2.45 - $6.700.00%
1166BIOMERICA INC.BMRA$1.38+3.85%5.85K$6.32M$1.27 - $2.940.00%
1167Critical Metals Corp.CRML$4.88-8.19%8.39M$716.08M$4.80 - $21.860.00%
1168Sana Biotechnology, Inc.SANA$2.02+0.25%2.97M$603.76M$1.86 - $5.490.00%
1169Quanterix CorporationQTRX$2.93+2.27%338.84K$138.71M$2.15 - $8.770.00%
1170Galectin Therapeutics Inc.GALT$3.06-2.87%135.38K$308.10M$2.02 - $7.130.00%
1171TriSalus Life Sciences, Inc.TLSI$2.42-3.97%372.41K$149.32M$2.20 - $7.950.00%
1172Phio Pharmaceuticals Corp.PHIO$0.79-5.03%62.94K$9.44M$0.75 - $1.880.00%
1173Santacruz Silver Mining LtdSCZM$6.83-3.12%301.89K$635.43M$5.61 - $17.640.00%
1174NewAmsterdam Pharma Company N.V.NAMS$20.16+1.03%1.56M$2.42B$17.90 - $42.200.00%
1175Quantum Computing Inc.QUBT$5.55-4.64%7.62M$1.26B$5.39 - $14.450.00%
1176Journey Medical CorporationDERM$4.26-2.05%376.48K$94.65M$4.17 - $9.550.00%
1177The Beachbody Company, Inc.BODI$3.38+2.58%68.72K$15.42M$3.16 - $16.870.00%
1178Ocular Therapeutix, Inc.OCUL$6.20-1.27%2.04M$1.36B$6.00 - $16.440.00%
1179Virgin Galactic Holdings, Inc.SPCE$1.83-30.34%37.30M$278.18M$1.81 - $8.900.00%
1180CLEANSPARK INC.CLSK$6.64-2.92%16.21M$1.71B$5.53 - $19.170.02%
1181Highway Holdings LtdHIHO$0.79+0.96%14.07K$3.65M$0.60 - $2.210.00%
1182Dream Finders Homes, Inc.DFH$10.65-3.18%859.99K$349.48M$7.30 - $21.550.01%
1183RxSight, Inc.RXST$5.33-1.49%478.70K$223.40M$4.11 - $13.220.00%
1184HUBSPOT, INC.HUBS$217.39+0.07%1.25M$10.62B$169.63 - $406.940.00%
1185SAGTEC GLOBAL LIMITEDSAGT$1.07+6.31%297.21K$22.98M$0.38 - $3.390.00%
1186Redwood Trust, Inc.RWT$2.90+0.35%3.02M$363.90M$2.69 - $6.970.31%
1187GPGI, Inc.GPGI$13.96-0.50%737.83K$4.05B$10.43 - $25.930.00%
1188Silvia, Inc.SVIA$2.60-2.44%369.44K$253.62M$2.56 - $4.990.00%
1189Bridgeline Digital Inc.BLIN$0.59-2.31%34.84K$7.45M$0.56 - $1.420.00%
1190Ideal Power Inc.IPWR$2.07-4.57%185.10K$34.05M$1.90 - $9.300.00%
1191Horizon Technology Finance CorporationHRZN$3.71-1.60%415.23K$241.58M$3.70 - $6.780.22%
1192Duos Technologies Group, Inc.DUOT$5.02-1.96%501.49K$147.26M$4.66 - $15.280.00%
1193Lands' End, Inc.LE$9.06+1.57%148.35K$267.55M$8.82 - $20.040.00%
1194DLH Holdings Corp.DLHC$3.28-1.14%7.09K$47.54M$3.27 - $6.880.00%
1195James River Group Holdings, Inc.JRVR$3.13+1.13%191.59K$144.99M$3.02 - $7.200.07%
1196Emergent Biosolutions, Inc.EBS$5.79-1.70%679.47K$296.77M$4.36 - $14.060.00%
1197OKYO Pharma LimitedOKYO$1.34-5.00%202.46K$70.38M$1.22 - $3.200.00%
1198Inspired Entertainment, Inc.INSE$4.39+0.11%391.51K$115.79M$3.10 - $9.950.00%
1199Tucows, Inc.TCX$11.75-5.27%87.40K$131.38M$8.45 - $25.170.00%
1200STELLUS CAPITAL INVESTMENT CORPORATIONSCM$6.75+1.20%323.27K$192.27M$6.54 - $13.550.23%

BTC $81K: Catch the Next Move

Track ETH, SOL & TON rotation signals

BTC $81K: Catch the Next Move

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
TPG Mortgage Investment Trust, Inc. (MITT) currently shows a 52-week decline of 45.38% as of 2026-11-13 23:09 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.