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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.09%⁩, the S&P 500 is ⁦-0.42%⁩, and the Nasdaq Composite is ⁦-0.91%⁩. Across individual stocks, 1,993 are advancing while 3,121 are declining, suggesting a mixed market tone.

Dow Jones
52,342.03
Change
+44.94+0.09%
S&P 500
7,560.87
Change
-31.53-0.42%
Nasdaq Composite
25,135.961
Change
-230.132-0.91%
24H Gainers
1,993
24H Losers
3,121

52 Week Gainers

#Stock52 Week Range
4601Oklo Inc.OKLO$23.92-4.10%5.84M$4.45B$18.54 - $115.720.00%
4602ZeroStack Corp.ZSTK$2.77+11.90%38.58K$60.55M$1.32 - $15.040.00%
4603TEN Holdings, Inc.XHLD$0.79-8.06%235.56K$13.29M$0.38 - $15.430.00%
4604CollPlant Biotechnologies LtdCLGN$4.61+10.73%124.47K$8.71M$2.64 - $22.500.00%
4605Richtech Robotics Inc.RR$0.76-7.00%8.04M$140.17M$0.74 - $5.600.00%
4606NextTrip, Inc.NTRP$0.96-11.95%95.86K$14.70M$0.90 - $4.710.00%
4607Soligenix, Inc.SNGX$0.32+1.01%135.19K$6.96M$0.28 - $1.700.00%
4608CervoMed Inc.CRVO$1.68-8.47%623.34K$25.32M$1.27 - $10.000.00%
4609Sow Good Inc.SOWG$1.94+0.80%5.37K$38.91M$1.04 - $15.900.00%
4610Locafy LimitedLCFY$0.88-2.97%38.18K$1.98M$0.85 - $6.200.00%
4611Estrella Immunopharma, Inc.ESLA$0.50-7.61%213.16K$21.92M$0.24 - $2.430.00%
4612Zenta Group Company LimitedZTG$0.43-12.38%70.10K$11.32M$0.43 - $12.250.00%
4613Lightbridge Corp.LTBR$4.10-3.53%395.38K$153.73M$3.91 - $20.340.00%
4614eXoZymes Inc.EXOZ$3.74-8.68%20.02K$34.84M$3.24 - $16.900.00%
4615Stratum Holdings Corp.SRTM$0.14+0.98%1.42M$202.22K$0.13 - $0.680.00%
4616Circle8 Group, Inc.CIRC$0.19-6.37%331.46K$21.85M$0.17 - $0.980.00%
4617Capstone Energy Plus, Inc.CEPL$2.66-6.83%303.95K$101.47M$2.26 - $12.330.00%
4618AETHLON MEDICAL INC.AEMD$5.29-6.27%25.90K$3.77M$1.41 - $25.660.00%
4619BitGo Holdings, Inc.BTGO$4.13+0.73%1.47M$525.03M$3.83 - $24.500.00%
4620Vistance Networks, Inc.VISN$4.23+5.88%10.49M$976.01M$3.90 - $19.951.40%
4621Alpha Compute Corp.ALP$3.11-1.92%40.24K$4.83M$2.78 - $27.900.00%
4622LanzaTech Global, Inc.LNZA$3.83-2.80%63.55K$50.13M$3.75 - $44.000.00%
4623Cosmos Holdings Inc.COSM$3.22-24.61%344.17K$324.04M$0.91 - $15.400.00%
4624DirectBooking Technology Co., LtdZDAI$1.36-5.86%2.03K$13.00M$1.10 - $12.000.00%
4625Defi Technologies, Inc.DEFT$0.32+6.82%3.00M$124.65M$0.30 - $1.700.00%
4626Xtend AI Robotics, Inc.XTND$1.37-3.69%1.71M$326.36M$0.80 - $7.150.00%
4627Antalpha Platform Holding CompanyANTA$2.16-1.50%13.48K$51.87M$1.50 - $11.190.00%
4628Maris-Tech Ltd.MTEK$0.28-2.22%324.68K$2.68M$0.21 - $2.820.00%
4629Atlas Critical Minerals CorporationATCX$1.94-0.77%6.57K$8.55M$1.85 - $14.010.00%
4630SL Science Holding LimitedSLBT$0.73-2.53%25.13K$405.09M$0.62 - $14.500.00%
4631Byrna Technologies, Inc.BYRN$3.83+0.26%114.02K$89.62M$3.17 - $20.690.00%
4632Energys Group LimitedENGS$0.35-25.13%5.94M$19.12M$0.35 - $5.000.00%
4633PowerCompute, Inc.PWCM$0.48-0.19%139.88K$1.21M$0.43 - $2.550.00%
4634Terrestrial Energy Inc.IMSR$2.60+4.00%2.07M$271.33M$2.40 - $13.530.00%
4635ASP Isotopes Inc.ASPI$1.74-7.22%3.60M$265.99M$1.66 - $8.880.00%
4636Full House Resorts, Inc.FLL$0.53-4.89%376.03K$19.26M$0.53 - $3.370.00%
4637BIO-key International, Inc.BKYI$2.10-18.22%207.77K$4.27M$1.55 - $11.100.00%
4638Tilray Brands, Inc.TLRY$2.44-2.41%2.38M$360.16M$2.42 - $15.700.00%
4639Natural Health Trends Corp.NHTC$0.76+2.61%46.20K$6.47M$0.70 - $4.000.65%
4640Odyssey Marine Exploration, Inc.OMEX$10.05-0.54%8.67K$23.60M$9.59 - $66.750.00%
4641aTyr Pharma, Inc.ATYR$6.11-0.97%36.04K$17.26M$4.07 - $44.400.00%
4642enCore Energy Corp.EU$0.55+0.80%2.18M$106.53M$0.53 - $3.670.00%
4643Intelligent Group LimitedINTJ$2.35-0.34%750$4.95M$2.16 - $12.520.00%
4644DNA X, Inc.SONM$2.17-7.88%14.00K$3.24M$2.02 - $11.020.00%
4645ThredUp Inc.TDUP$1.56+4.00%1.36M$176.51M$1.24 - $8.760.00%
4646Quantum Biopharma LtdQNTM$1.60-8.29%80.38K$6.13M$1.34 - $12.420.00%
4647Rail Vision Ltd.RVSN$2.19-5.24%6.65K$4.81M$2.07 - $12.580.00%
4648Dogwood Therapeutics, Inc.DWTX$1.14+1.34%74.49K$43.43M$0.90 - $7.040.00%
4649Kestrel Group, Ltd.KG$3.39-5.39%5.53K$33.38M$3.39 - $16.390.00%
4650BioHarvest Sciences Inc.BHST$1.50-10.95%9.81K$24.72M$1.37 - $8.300.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Oklo Inc. (OKLO) currently leads with a 52-week gain of 76.47% as of 2026-11-13 22:21 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.