Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More
100%+ PoR

52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.10%⁩, the S&P 500 is ⁦-0.40%⁩, and the Nasdaq Composite is ⁦-0.91%⁩. Across individual stocks, 1,981 are advancing while 3,133 are declining, suggesting a mixed market tone.

Dow Jones
52,347.55
Change
+50.46+0.10%
S&P 500
7,561.67
Change
-30.73-0.40%
Nasdaq Composite
25,136.273
Change
-229.82-0.91%
24H Gainers
1,981
24H Losers
3,133

52 Week Gainers

#Stock52 Week Range
3251IPG Photonics CorporationIPGP$67.87-4.35%177.33K$2.89B$61.59 - $155.820.00%
3252Quantum Cyber N.V.QUCY$0.63+11.37%501.62K$14.34M$0.30 - $4.930.00%
3253Madrigal Pharmaceuticals, Inc.MDGL$427.54+0.54%400.61K$9.93B$353.54 - $615.000.00%
3254Lightspeed Commerce Inc.LSPD$10.21+1.19%360.31K$1.36B$7.83 - $12.820.00%
3255Sylvamo CorporationSLVM$38.55-0.10%195.24K$1.53B$30.40 - $56.800.05%
3256Stryker CorporationSYK$309.58-0.88%2.76M$117.85B$267.00 - $389.330.01%
3257Red Rock Resorts, Inc.RRR$48.86-0.71%629.32K$2.91B$46.29 - $68.990.04%
3258Bluerock Private Real Estate FundBPRE$12.18+1.16%710.22K$0$11.67 - $18.270.00%
3259Millrose Properties, Inc.MRP$25.87+0.78%1.50M$4.32B$21.07 - $32.590.12%
3260Morgan Stanley Direct Lending FundMSDL$13.85+0.07%607.31K$1.16B$12.71 - $17.910.00%
3261Monopar Therapeutics Inc.MNPR$72.00-1.45%189.55K$483.28M$50.07 - $124.820.00%
3262Sabine Royalty TrustSBR$64.34-0.05%23.22K$938.02M$63.87 - $79.860.00%
3263Shoe Station Group, Inc.SHOE$14.36+1.13%221.80K$390.36M$10.20 - $17.740.05%
3264Global Net Lease, Inc.GNL$6.58-1.64%3.44M$1.47B$6.55 - $10.040.14%
3265Sixth Street Specialty Lending, Inc.TSLX$17.63+0.46%283.02K$1.69B$16.04 - $22.840.09%
3266CRISPR Therapeutics AGCRSP$42.21-0.93%1.61M$4.09B$41.79 - $63.450.00%
3267Xilio Therapeutics, Inc.XLO$8.11+1.87%7.54K$53.36M$6.47 - $11.300.00%
3268GMR Solutions Inc.GMRS$11.54+2.12%1.51M$784.37M$8.99 - $15.980.00%
3269Inogen Inc.INGN$5.68+1.16%189.62K$150.66M$5.04 - $7.670.00%
3270Gentex Corp.GNTX$19.20-0.90%2.57M$4.09B$19.20 - $26.480.03%
3271Ryan Specialty Holdings, Inc.RYAN$46.88+1.60%1.91M$5.61B$29.28 - $58.910.01%
3272Quantum-Si IncorporatedQSI$1.15-6.56%3.27M$227.99M$0.69 - $1.810.00%
3273Liberty Capital CorporationGLIBK$27.37-3.70%290.59K$1.13B$19.30 - $41.170.00%
3274ICL Group Ltd.ICL$4.52-1.53%878.85K$5.90B$4.35 - $6.970.04%
3275Cameco CorporationCCJ$70.72-1.61%2.86M$30.80B$66.06 - $135.240.00%
3276Hancock Whitney CorporationHWCPZ$19.64-0.36%7.50K$0$19.64 - $24.580.00%
3277XPLR Infrastructure, LPXIFR$7.61+3.54%2.33M$716.94M$7.11 - $13.250.26%
3278Amrize LtdAMRZ$40.90+0.15%1.71M$22.16B$35.78 - $65.940.02%
3279Xcel Energy Inc.XELLL$20.47-2.15%78.20K$0$20.40 - $25.220.00%
3280Clean Energy Fuels Corp.CLNE$1.82-8.08%1.37M$401.69M$1.32 - $2.840.00%
3281VICI Properties Inc.VICI$25.01+0.85%6.17M$27.54B$22.43 - $30.830.07%
3282AdaptHealth Corp.AHCO$7.66-2.67%1.60M$1.05B$5.21 - $13.430.00%
3283Celestica, Inc.CLS$240.28-8.04%3.30M$30.30B$197.50 - $474.020.00%
3284Huntington Bancshares IncorporatedHBANZ$17.38-1.19%12.75K$0$17.30 - $22.230.00%
3285National Health InvestorsNHI$62.99-2.48%341.10K$3.09B$62.75 - $91.380.06%
3286Azora Therapeutics, Inc.AZR$4.00+5.08%10.14K$9.22M$3.02 - $4.970.00%
3287Fulton Financial CorporationFULTP$16.09-1.08%10.88K$128.76M$15.31 - $19.770.00%
3288Forward Air Corp.FWRD$17.38+1.34%350.07K$549.52M$7.86 - $31.180.00%
3289Orion S.A.OEC$3.99+0.50%382.68K$225.75M$3.84 - $8.640.02%
3290Stantec, Inc.STN$85.67+14.06%892.10K$9.48B$65.35 - $108.400.01%
3291Lyell Immunopharma, Inc.LYEL$14.24-8.86%202.15K$350.12M$7.20 - $45.000.00%
3292Liberty Capital CorporationGLIBA$27.20-3.39%49.56K$1.13B$19.30 - $41.870.00%
3293Jefferies Financial Group Inc.JEF$45.68-1.25%1.42M$8.64B$35.53 - $66.590.03%
3294RHRH$129.38+0.17%405.99K$2.45B$106.30 - $239.400.00%
3295Albemarle CorporationALB$93.53-1.39%938.38K$11.04B$89.77 - $221.000.03%
3296Csquare, Inc.CSQR$16.87-2.03%1.60M$2.84B$12.30 - $23.500.00%
3297Palmer Square Capital BDC Inc.PSBD$9.81-0.31%65.91K$295.63M$9.34 - $12.450.00%
32981-800-FLOWERS.COM Inc.FLWS$2.52-3.45%354.87K$93.78M$2.33 - $5.230.00%
3299Ellington Financial Inc.EFC$11.11+0.91%1.61M$1.43B$10.84 - $14.120.14%
3300INNOVATE Corp.VATE$4.56-5.97%79.40K$62.18M$3.75 - $21.300.03%

BTC $81K: Catch the Next Move

Track ETH, SOL & TON rotation signals

BTC $81K: Catch the Next Move

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
IPG Photonics Corporation (IPGP) currently leads with a 52-week gain of 16.90% as of 2026-11-14 00:23 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.