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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.09%⁩, the S&P 500 is ⁦-0.42%⁩, and the Nasdaq Composite is ⁦-0.91%⁩. Across individual stocks, 1,994 are advancing while 3,120 are declining, suggesting a mixed market tone.

Dow Jones
52,342.03
Change
+44.94+0.09%
S&P 500
7,560.87
Change
-31.53-0.42%
Nasdaq Composite
25,135.961
Change
-230.132-0.91%
24H Gainers
1,994
24H Losers
3,120

52 Week Gainers

#Stock52 Week Range
4951Actuate Therapeutics, Inc.ACTU$0.29-2.87%174.06K$6.87M$0.27 - $7.900.00%
4952Tianci International, Inc.CIIT$1.96+16.37%85.38K$2.31M$1.52 - $52.500.00%
4953Vistagen Therapeutics, Inc.VTGN$0.18+0.84%395.96K$8.03M$0.16 - $5.140.00%
4954Solmate Infrastructure Public Limited CompanySLMT$3.24+0.15%41.24K$27.14M$2.70 - $78.000.00%
4955Cango Inc.CANG$1.52-5.03%532.15K$63.99M$0.88 - $34.000.00%
4956Akanda Corp.AKAN$1.37+103.22%71.50M$3.27M$0.64 - $78.900.00%
4957Future FinTech Group Inc.FTFT$4.14+6.68%52.21K$35.92M$1.22 - $90.870.00%
4958Jyong Biotech Ltd.MENS$1.77+2.38%26.46K$134.87M$1.43 - $40.250.00%
4959E-Home Household Service Holdings LimitedEJH$1.11+1.27%9.14K$3.56M$1.00 - $26.500.00%
4960Veraxa Biotech AGVRXA$1.11-2.61%112.38K$178.17M$0.90 - $27.360.00%
4961Evolution Metals & Technologies Corp.EMAT$0.93-6.25%1.01M$585.81M$0.89 - $24.090.00%
4962Nexalin Technology, Inc.NXL$1.52+3.36%16.50K$1.83M$1.31 - $39.300.00%
4963Tempest Therapeutics, Inc.TPST$0.38-0.26%150.07K$7.64M$0.34 - $9.750.00%
4964Nocera, Inc.NCRA$1.44+1.19%4.68K$3.59M$1.29 - $39.900.00%
4965Ernexa Therapeutics Inc.ERNA$1.68-7.69%26.69K$2.74M$1.68 - $40.240.00%
4966Artelo Biosciences, Inc.ARTL$2.06-5.21%13.84K$1.13M$1.91 - $179.190.00%
4967TNL MediageneTNMG$2.68-0.48%6.70K$2.27M$2.45 - $92.880.00%
4968Getty Images Holdings, Inc.GETY$0.08-40.95%27.99M$0$0.00 - $3.210.00%
4969Olenox Industries Inc.OLOX$0.58-7.42%221.87K$962.42K$0.57 - $21.900.00%
4970Vivos Therapeutics, Inc.VVOS$0.10-0.73%714.51K$3.22M$0.09 - $2.690.00%
4971Datavault AI Inc.DVLT$0.06+3.37%18.39M$59.92M$0.05 - $2.700.00%
4972Auddia Inc.AUUD$0.35+10.47%13.49M$2.04M$0.21 - $11.470.00%
4973Greenlane Holdings, Inc.GNLN$0.88-5.04%25.84K$613.28K$0.83 - $27.920.00%
4974OFA GroupOFAL$2.52-7.81%75.06K$1.95M$1.82 - $90.930.00%
4975Innventure, Inc.INV$0.13-16.11%5.38M$14.66M$0.10 - $7.860.00%
4976GRI Bio, Inc.GRI$1.72-4.13%21.68K$3.75M$1.36 - $64.120.00%
4977Triller Group Inc.ILLR$0.19-18.65%3.40M$0$0.01 - $7.960.00%
4978VS Media Holdings LimitedVSME$1.03+28.05%219.32K$4.69M$0.58 - $30.800.00%
4979Rich Sparkle Holdings LimitedANPA$1.07-6.87%10.94K$17.67M$1.00 - $180.640.00%
4980MDxHealth SAMDXH$0.14+2.71%2.00M$13.98M$0.11 - $4.350.00%
49813 E Network Technology Group LtdMASK$1.83-2.16%9.57K$2.40M$1.50 - $66.530.00%
4982Agroz Inc.AGRZ$1.79-7.37%11.29K$2.13M$1.68 - $105.680.00%
4983Maison Solutions Inc.MSS$0.91-11.20%137.61K$737.59K$0.85 - $29.000.00%
4984707 Cayman Holdings LimitedJEM$2.59+5.42%17.34K$1.72M$2.21 - $135.240.00%
4985Moleculin Biotech, Inc.MBRX$7.91-1.19%9.74K$8.26M$3.23 - $243.800.00%
4986VenHub Global, Inc.VHUB$0.22+6.50%82.69K$21.40M$0.21 - $40.300.00%
4987Tenon Medical, Inc.TNON$1.42-20.95%182.27K$3.80M$1.39 - $44.800.00%
4988Cloudastructure, Inc.CSAI$1.40-5.88%41.32K$1.39M$1.40 - $46.800.17%
4989Trident Digital Tech Holdings LtdTDTH$0.67-12.65%264.78K$19.47M$0.56 - $20.850.00%
4990Dogness (International) CorporationDOGZ$0.37+0.11%15.48K$3.17M$0.33 - $13.000.00%
4991IceCure Medical Ltd.ICCM$0.72+4.21%20.84K$2.46M$0.65 - $22.500.00%
4992Children's Place, Inc.PLCE$0.29-35.74%12.04M$6.38M$0.15 - $9.300.00%
4993INVO Fertility, Inc.IVF$2.62-0.57%25.84K$3.21M$1.59 - $91.600.00%
4994Pop Culture Group Co., LtdCPOP$2.94-3.77%8.29K$2.75M$2.47 - $382.500.00%
4995Powell Max LimitedPMAX$0.64-12.88%85.92K$837.32K$0.45 - $33.500.00%
4996Basel Medical Group LtdBMGL$0.46-16.44%608.82K$9.29M$0.46 - $17.700.00%
4997BSLK$0.000.00%0$0$0.00 - $2.330.00%
4998PRPH$0.000.00%0$0$0.00 - $3.000.00%
4999Dragonfly Energy Holdings Corp.DFLI$1.80-14.86%124.59K$3.78M$1.66 - $78.660.21%
5000YYForce Inc.YFOR$0.04-10.31%53.88M$316.60K$0.04 - $2.050.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Actuate Therapeutics, Inc. (ACTU) currently leads with a 52-week gain of 95.14% as of 2026-11-13 21:32 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.